Neuronal plasticity and neurotrophic factors in drug responses
نویسندگان
چکیده
منابع مشابه
Neurotrophic factors and synaptic plasticity
Models of activity-dependent synaptic plasticity, whether in the context of development or of learning and memory, have long postulated the existence of extracellular signal-ing molecules that enhance and stabilize active synapses. In recent years, neurotrophic factors have emerged as attractive candidates for such signaling molecules. The work of several laboratories has shown that neurotrophi...
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15 صفحه اولNeuronal differentiation factors/cytokines and synaptic plasticity.
As in the hematopoietic system, the enormous variety of phenotypes in the nervous system arises, in part, through the action of instructive differentiation signals. Such signals include secreted and cell-bound proteins as well as steroid hormones. Since these agents have broad effects on cell proliferation and gene expression in many different tissues, the term cytokines is being adopted for th...
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context the current study aimed to review research articles concerning cortical representational plasticity following the manipulations of inputs. evidence acquisition this review article compromised previous studies in pubmed, google scholar and scientific information databases according to the keywords since 1988. results ca1 neurons depolarization paired with ca3 presynaptic input result in ...
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Functional and structural neuronal plasticity are mediated by a complex network of biochemical signal transduction pathways that control the strength of specific synapses and the formation of new synapses de novo. The neuronal protein kinase Cdk5 has been implicated as being involved in numerous aspects of both functional and structural plasticity through its regulation of signal transduction p...
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ژورنال
عنوان ژورنال: Molecular Psychiatry
سال: 2017
ISSN: 1359-4184,1476-5578
DOI: 10.1038/mp.2017.61